Liver Transplant

Liver Cancer Specialist Singapore
Liver Transplant
By Dr. Lee Ser Yee
Liver transplantation is the standard of care for patients with end-stage liver diseases, acute liver failure and selected cases of liver cancer (hepatocellular carcinoma). The most common reason for a liver transplant in adults is cirrhosis and/or liver cancer. Cirrhosis is scarring of the liver that prevents the liver from working well and can worsen to liver failure.

The most common causes of cirrhosis are:

  • Long-term infection with Hepatitis B and/or Hepatitis C
  • Long-term alcohol abuse
  • Non-alcoholic fatty liver disease
  • Liver damage from poisoning or medicines
  • Problems with the drainage system of the liver (the biliary tract) e.g., primary biliary cirrhosis or primary sclerosing cholangitis
  • Metabolic disorders of copper or iron (Wilson disease and hemochromatosis)
  • Other less common causes include - Autoimmune conditions, polycystic liver disease

Liver transplantation replaces a diseased liver with a healthy liver. The new liver may be from a donor who has recently died (deceased donor) or a healthy living donor.

In adult living-donor liver transplant, a healthy person will donate part of his or her liver to a person with a diseased liver. The remnant liver can regenerate and both the patient and donor will end up with fully functional livers after a successful transplant.

For patients waiting for a life-saving liver transplant, living donor liver transplantation offers many benefits including shorter wait time, faster recovery, and better outcomes compared to deceased donor liver transplant.

Advancements in immunosuppression, medical management and surgery techniques have led to significant improvement in this field, achieving long term success and good outcomes.

It takes a village…

About Dr. Lee Ser Yee and the Mount Elizabeth Liver Transplant team.

Dr. Lee is a double USA-fellowship trained Hepatopancreatobiliary and Liver Transplant surgeon. He is a Ministry of Health, Singapore (MOH) gazetted and Board-accredited Liver Transplant surgeon. He trained as a Hepatopancreatobiliary and Liver Transplant fellow for more than a year in New York-Presbyterian Hospital, which is an international leader in the organ transplantation with the most transplant surgeries performed in the United States.

Our multidisciplinary liver transplant team in Mount Elizabeth is the only private liver transplant centre in Singapore.

Our focus is on optimizing your overall health while waiting for a liver, minimizing your time on the waitlist, and achieving optimal long-term health outcomes with a good quality of life. Our team includes a dedicated transplant coordinator, transplant surgeons, hepatologists (physicians who specialise in liver disease), critical care specialists, psychiatrists as well as a strong nursing and allied health team (pharmacists, nutritionists, physiotherapist, social workers).

Liver transplantation requires life-long care. Our compassionate team provides personalized care every step of the journey—from the uncertainty of waiting for a liver, to the hospital stay and your long-term follow-up care. We partner closely with you and your family with the goals of helping you spend less time in the hospital and more time living life.

Find out more here.

Singapore Liver Surgeon
Dr Lee Ser Yee

Senior Consultant Hepatopancreatobiliary Surgeon

MBBS, MMed (Surgery), MSc, FAMS, FRCSEd

Prior to private practice, Dr Lee Ser Yee was a founding member and Senior Consultant at the Department of Hepatopancreatobiliary (HPB) and Transplant Surgery at Singapore General Hospital (SGH). He served as the Director of the Laparoscopic programme and the Director of the Surgical Skills Training Program and the SingHealth Surgical Skills Centre.

He started his medical training at the National University of Singapore in 1996 and completed his training in General Surgery, HPB surgery and Liver Transplantation at SGH and National Cancer Centre, Singapore.

He also completed dual USA-fellowships in Advanced Laparoscopic HPB surgery and Liver Transplantation under Professor Daniel Cherqui at the New York Presbyterian Hospital-Weill Cornell Medical Center and a Complex Surgical Oncology clinical fellowship at Memorial Sloan Kettering Cancer Center in New York.

Liver Surgeon Singapore
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